The four regional group champions play off over two legs for two of the promotion spots. First leg matches are as follows:
| 17 May | Cartagena Héctor Yuste, Samuel |
2-1 | Alcoyano Fernando Martín |
| 17 May | Cádiz Toedtli |
1-0 | Real Unión |
The remaining twelve teams who finished in the top four of the regional groups enter a knock-out stage, with the winners of the six games entering a second round together with the two losers of the above two ties.
| 16 May | Sabadell Pradas |
1-1 | Cultural Leonesa Iván Mateo |
| 17 May | Sant Andreu |
0-0 | Alcorcón |
| 17 May | Leganés Javi Vicente, Mario |
2-2 | Jaén Arriaga, Esparza |
| 17 May | Marbella |
0-2 | Lorca Jairo, Elías |
| 17 May | Zamora |
0-2 | Villarreal B Matilla, Barodia (OG) |
| 17 May | Poli Ejido |
0-0 | Ponferradina |
The four sides who finished fifth from bottom in the regional groups have to play-off to avoid the remaining two relegation spots.
| Terrassa Raúl Pérez, Curto |
2-0 | Antequera |
|
| Las Palmas B |
0-0 | Sporting B |